Research Lead (Formulation Sciences), London

Isomorphic Labs is seeking a Research Lead in Formulation Sciences to join their London-based team. The company leverages advanced AI technologies to accelerate drug discovery and development, aiming to revolutionize the pharmaceutical industry. This role is integral to the Drug Design and Medical Research function, focusing on the progression of drug discovery and preclinical development projects.

In this position, the Research Lead will develop and execute comprehensive pre-formulation strategies for small molecules, collaborating closely with drug design, pre-clinical, and CMC functions. Responsibilities include designing innovative formulation technologies to optimize solubility, stability, and manufacturability, as well as conducting stability studies using ICH and ASAP methodologies. The role also involves authoring technical reports, protocols, and regulatory submissions in alignment with internal policies and global regulatory requirements.

Candidates should possess a PhD in pharmaceutical science or a related technical field, with over six years of professional experience in a biotech or pharmaceutical setting. Expertise in developing oral solid dosage forms and supporting IND packages is essential. A deep understanding of preformulation, manufacturing processes, and advanced drug delivery technologies is required, along with knowledge of global regulatory guidelines, including ICH and FDA. Strong communication, interpersonal, and influencing skills are necessary for effective collaboration within cross-functional teams.

While not mandatory, specialized knowledge and practical experience in the development of amorphous dispersions would be advantageous.

Isomorphic Labs fosters a culture of curiosity, creativity, and care, encouraging rigorous and future-focused science. The company values initiative, integrity, and a determined approach to achieving its mission of solving all diseases through AI. Collaboration is key, with an emphasis on connection and teamwork across various fields to make a real impact on global health.