Sr. Associate Scientist I / II – High Throughput Chemistry
JOB SUMMARY
We are seeking a motivated and detail-oriented Sr. Associate Scientist to join our Discovery Chemistry team at Iambic Therapeutics in San Diego, CA. In this role, the successful candidate will apply hands-on synthetic chemistry skills to execute high-throughput experiments and support compound library campaigns. Candidates will be leveled based on experience, technical depth, and demonstrated independence. The successful candidate will work cross-functionally with broader chemistry, biology, compound management, AI/ML, and software teams across the discovery pipeline, leveraging Iambic's HTE platform to accelerate our programs. This position will be based in our San Diego Headquarters.
KEY RESPONSIBILITIES
- Execute parallel synthetic chemistry experiments in support of compound library campaigns.
- Execute and refine standard company procedures and synthetic methods to ensure high success rate and project impact.
- Operate, maintain, and calibrate laboratory automation and analytical/purification equipment used in the HTE workflow.
- Collaborate with senior chemists and cross-functional partners to adapt bench-scale synthetic routes to automation-compatible, high-throughput processes.
- Record, organize, and analyze experimental and library compound data; communicate results clearly to project teams.
- Ensure all laboratory work follows established safety protocols and best practices for ELN data recording.
- Identify bottlenecks in existing processes and contribute to solutions that ensure business continuity.
QUALIFICATIONS
Required:
- MS degree in Organic Chemistry with 3+ years of experience or BS in Organic Chemistry with 5+ years of industry experience.
- Strong foundation in modern organic synthetic methods.
- Direct experience with High Throughput Chemistry and/or Parallel Synthesis.
- Familiarity with laboratory automation, liquid handling robotics, and automated analytical/purification systems, and high adaptab...