Scientist II, Analytical Development, Flow, Function and Bioanalytical Assays
Legend Biotech is seeking a Scientist II to join the Flow Cytometry and Functional Assays team within the Analytical Development organization. This role focuses on developing and qualifying flow cytometry-based methods, cell-based potency assays, and other bioanalytical strategies to support the release, characterization, and stability assessment of cell therapy products. The position is based in Somerset, New Jersey, and reports directly to a Principal Scientist in the Analytical Development team.
Key responsibilities include developing and optimizing assays such as potency (cell-based), flow cytometry, and bioanalytical assays like ELISA. The Scientist II will also develop and qualify analytical methods for lentiviral vector characterization, including infectious titer assays and vector-specific flow cytometry panels. Additional duties involve transferring methods to Quality Control (QC), performing assay pre-qualification and qualification activities, generating standard operating procedures (SOPs), and collaborating cross-functionally with Process Development, QC, and Manufacturing teams.
The ideal candidate holds a Ph.D. or Master's degree in a scientific discipline or engineering, with 2-5 years of related experience, which may include post-doctoral work. Expertise in analytical method development and qualification/validation is required, along with experience in developing multicolor flow cytometry methods, cell culture, potency assays, cytotoxicity assays, cytokine release assays, immunoassays, and infectious titer assays. A solid understanding of ICH guidelines and regulatory expectations for method qualification is essential.
Legend Biotech offers a comprehensive benefits package, including medical, dental, and vision coverage, generous paid leave, and a 401(k) plan. The company emphasizes employee well-being through programs supporting mental health, financial health, community engagement, and physical health. Competitive compensation structures are designed to recognize and reward employees for their contributions.
Joining Legend Biotech means becoming part of a global biotechnology company dedicated to treating and potentially curing life-threatening diseases. The company fosters a culture driven by core behaviors such as ownership and commitment, agility and prioritization, teamwork and communication, and continuous improvement. Employees have access to continuous learning and development opportunities, including on-demand professional learning and leadership development classes.